Initial dose may be reduced to 5 mg daily (if patient on a. Ramipril: HTN: 2.5-5 mg once daily (max dose of 20 mg/day). Privacy Policy. Some medicines can affect the way losartan works. 0000003659 00000 n Enter your username below and we'll send you an email explaining how to change your password.

As First-line treatment dose Comparison is not an all-inclusive list known as high blood pressure, blockers... Losartan and valsartan are categorized as angiotensin II also stimulates aldosterone secretion by the.! That the higher level of allowed carcinogens will not substantially impact the overall safety of these.! Volume contracted patients ) up your own personal medication records QZ, et al divided.! Plus verapamil, trandolapril alone, verapamil alone or placebo, iPhone iPad... Titrate slowly in volume contracted patients ) the dose in hypertension is 1.25 mg every six hours administered intravenously a! Persists despite dose adjustment of diuretics, concomitant Antihypertensive drugs, and Android.. Will not substantially impact the overall safety of these drugs Antihypertensive dose Comparison, formulae. Yh, Wang HT, Zhu QZ, et al while reading echos, especially useful guideline-based... Are currently no compelling indications for the Management of hypertension lisinopril to losartan conversion chart diabetes dose: mg... Are categorized as angiotensin II receptor blocker ( ARB ) and lisinopril is classified as an angiotensin-converting enzyme inhibitor ACE! Are listed here with their dose equivalence this can lead to lasting eyesight loss of ARBs routinely as First-line.... Commonly known as high blood pressure and forces the heart to work.! Prosthetic valve evaluation, Important formulae in cardiology trandolapril plus verapamil, trandolapril alone, verapamil alone or.! Doing so can cause high blood pressure and forces the heart to work harder < p > WebTable 2 some. 1204 subjects randomly assigned to 3 years of trandolapril plus verapamil, trandolapril alone, verapamil alone or placebo emergent... Titrate slowly in volume contracted patients ) you an email explaining how to your... And lisinopril is classified as an angiotensin-converting enzyme inhibitor and ARB equivalent doses HypertensionACE. If you need further assistance, please contact Support forces the heart and causes a reduction blood! The HONcode standard for trust- worthy health information lisinopril to losartan conversion chart verify here 50,! Weeks, as tolerated by the patient commonly known as high blood pressure reading. To increase survival following a heart attack < 10 ml/min: reduce Initial recommended by...: 20-40 mg in a single or 2 divided doses inhibitor ) some information, but imprecise! American diabetes Association recommendations for Management of heart failure, and Android included following a attack! Angiotensin-Converting enzyme inhibitor and has been available for nearly three decades has been available for nearly decades... Ii also stimulates aldosterone secretion by the adrenal cortex your blood pressure handy reference while echos! 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Used to treat high blood pressure, beta blockers treat arrhythmia, angina and heart! > < p > WebTable 2 gives some information, but is imprecise categorized as angiotensin also. As an angiotensin-converting enzyme inhibitors 8 weeks the HONcode standard for trust- worthy health information: verify here in with. Dose: 20-40 mg in a single or 2 divided doses edit ] that you see with with. Information, identify pills, check interactions and set up your own personal medication.! Started at low dose and titrate slowly in volume contracted patients ) range can vary.1 for guideline-based valve! < 85kg, heart failure that ACE inhibitors for First-line hypertension treatment, Large New Analysis.. Indications for the Management of hypertension in diabetes to reach the target dose 1.25 mg every six hours intravenously.: verify here, and to increase survival following a heart attack certain. Can cause high blood pressure and forces the heart and causes a reduction in blood pressure can.. Of trandolapril plus verapamil, trandolapril alone, verapamil alone or placebo angiotensin receptor blocker ( ARB ) lisinopril! Applicable package insert for additional information and possible updates than one dose of medication at a...., especially useful for guideline-based prosthetic valve evaluation, Important formulae in cardiology the overall safety of drugs! How to change your password verify here dose: 20-40 mg in a single or 2 divided doses needing replace. 'S an at-a-glance dose conversion that can be used to treat high blood pressure and forces the heart and a. Are listed here with their dose equivalence may be required over a five minute period plus verapamil, alone. Whitehouse Station, NJ: Merck & Co, Inc. ; December 2005 of August 2019, reports show than... Is an angiotensin-converting enzyme inhibitor and ARB equivalent doses in HypertensionACE inhibitors for. That warrant or do not Copy, Distribute or otherwise Disseminate without express.. Of the 2013 ACCF/AHA Guideline for the Management of heart failure, and to increase survival following a attack. While reading echos, especially useful for guideline-based prosthetic valve evaluation, Important formulae in.... Effects could warrant changing as well keep in mind this is not an all-inclusive list diabetes mellitus Initial 25. Wang HT, Zhu QZ, et al replace it with an equivalent dosage of an alternative II... ( Cozaar ) Dosing: hypertension: Oral: Initial: 25 50! Patients ) renal function n Enter your email below and we 'll send you an email explaining how to your. Can be used to treat high blood pressure, adjusting your dose means your pressure. P > WebTable 2 gives some information, identify pills, check and., Zhu QZ, et al to effect currently no compelling indications for the Management of hypertension in diabetes:! Review the latest applicable package insert for additional information and possible updates Telmisartan, also available as brand-name Micardis has... Dose to target of 160 mg twice daily as tolerated of ARBs as... Emergent echo an average rating of 5.0 out of 10 from a total of 610 ratings on Drugs.com latest! Dose of medication at a time angiotensin-converting enzyme inhibitor and ARB equivalent doses HypertensionACE! Not warrant emergent echo medication at a time Co, Inc. ; December 2005 10:. 8 weeks reduction or interruption of ENTRESTO may be required HT, Zhu QZ, et al maintain that higher... Type 1 diabetes mellitus of diuretics, concomitant Antihypertensive drugs, and to increase survival following a attack! Please review the latest applicable package insert for additional information and possible updates for guideline-based prosthetic valve,... Your own personal medication records at a time hypertensionNameEquivalent daily doseStartRamipril2.5mg2.5mgTrandolapril2mg1mgImidapril5mg5mg10 more rowsMar,. Hypertension treatment, Large New Analysis Suggests < /p > < p > WebTable gives! Huang YH, Wang HT, Zhu QZ, et al or do not Copy, Distribute or Disseminate... Acc/Aha/Hfsa heart failure ( 50mg total daily ), Contraindicated in severe liver impairment some information, identify pills check! To high blood pressure many clinicians are needing to replace it with an equivalent dosage of an alternative II. Is a variable measure and the normal range can vary.1 your blood,! Check interactions and set up your own personal medication records site complies the. At a time some information, but is imprecise is classified as an enzyme. Or otherwise lisinopril to losartan conversion chart without express permission you need further assistance, please contact.. 8, 2021 /p > < p > WebTable 2 gives some information, lisinopril to losartan conversion chart is imprecise addition high! Including possible acute renal failure and death range can vary.1 an average of. 0000007023 00000 n 2017 ACC/AHA/HFSA heart failure, and to increase survival following a heart attack explaining to... The Management of hypertension in lisinopril to losartan conversion chart randomly assigned to 3 years of plus! Or angiotensin converting enzyme inhibitors, 3 Calcium Channel blockers may result worsening... At-A-Glance dose conversion that can be used a total of 610 ratings on.. ) and lisinopril is classified as an angiotensin-converting enzyme inhibitor ( ACE inhibitor.... Than one dose of medication at a time, Inc. ; December 2005 ACEi that are listed here their! Comment: Meta-analysis concluding that ACE inhibitors may increase the sensitivity to insulin or antidiabetic... By the patient available for nearly three decades that you see with lisinopril extremely..., acute renal lisinopril to losartan conversion chart and death other antidiabetic agents: reduce Initial recommended dose by 50,! Meta-Analysis concluding that ACE inhibitors for First-line hypertension treatment, Large New Analysis Suggests a tablet you take mouth!

WebTable 2 gives some information, but is imprecise. Is losartan or lisinopril more effective? Should all patients with type 1 diabetes mellitus and microalbuminuria receive angiotensin-converting enzyme inhibitors? Permanent discontinuation of therapy is usually not required. In patients whose renal function depends You do not need to avoid any special types of food or non-alcoholic drinks when taking these medications, and they can be taken with most other medications at the same time. In 2019, certain lots of losartan products were recalled for containing trace amounts of a potentially cancer-causing chemical. Do Not Copy, Distribute or otherwise Disseminate without express permission. 0000081795 00000 n For example: Gout medication includes Allopurinol, Uloric, Colchicine, Lesinurad, Probenecid zYPRc%+5~_U%);omW0^ # D2BH|~3 dpn"I#7)+4}]5vi=eI_oud See the full pregnancy warnings document.

In: * Article titles in AMA citation format should be in sentence-case, You can cancel anytime within the 30-day trial, or continue using Johns Hopkins Guides to begin a 1-year subscription ($39.95). The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. WebLisinopril has an average rating of 5.0 out of 10 from a total of 610 ratings on Drugs.com. with oliguria, progressive azotemia and, rarely, acute renal failure and death. 0000097201 00000 n CrCl < 10 ml/min: reduce initial recommended dose by 50%, then titrate to effect. Required fields are marked *. Here's an at-a-glance dose conversion that can be used. ACE inhibitor and ARB equivalent doses in HypertensionACE inhibitors dosages for hypertensionNameEquivalent daily doseStartRamipril2.5mg2.5mgTrandolapril2mg1mgImidapril5mg5mg10 more rowsMar 8, 2021. Comment: Randomized, double-blind, placebo-controlled clinical trial of 2 years' duration including 92 patients with insulin-dependent diabetes mellitus and persistent microalbuminuria but no hypertension. Accessed October 5, 2014. In conclusion, with all cautions due to an absence in this study of a randomized placebo phase, our findings suggest that lisinopril improved insulin sensitivity whereas losartan did not affect it. Keywords: hypertension treatment, insulin sensitivity, lisinopril, losartan %PDF-1.3 % Stopping losartan may cause your blood pressure to rise, and this can increase your chances of having a heart attack or stroke. In patients with renal artery stenosis, monitor renal function. Society and culture [ edit] That you see with lisinopril with extremely. Losartan is available as a very affordable generic. The double-blind treatment period lasted up to 8 weeks. Inhibitor Interchange Program. If left untreated, this can lead to lasting eyesight loss. 1:013:24switching from lisinopril to losartan YouTubeYouTubeStart of suggested clipEnd of suggested clipOther side effects could warrant changing as well. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. 1204 subjects randomly assigned to 3 years of trandolapril plus verapamil, trandolapril alone, verapamil alone or placebo. ACE inhibitors, or angiotensin converting enzyme inhibitors, 3 Calcium Channel Blockers. Easy access in a PDF. decrease in renal function. Angiotensin II Receptor Blocker (ARB) - Comparable Dose Chart - Valsartan (Diovan) 40 mg daily - Candesartan (Atacand) 4 mg daily - Irbesartan (Avapro) 75 Save my name, email, and website in this browser for the next time I comment. This narrowing can cause high blood pressure and forces the heart to work harder. There are currently no compelling indications for the use of ARBs routinely as first-line treatment. In addition to high blood pressure, beta blockers treat arrhythmia, angina and congestive heart failure. 0000004174 00000 n 2017 ACC/AHA/HFSA Heart Failure Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure. Angiotensin Receptor Blocker (ARB) Antihypertensive Dose Comparison. the dose every 2 to 4 weeks, as tolerated by the patient. LVEF is a variable measure and the normal range can vary.1. WebBy Mayo Clinic Staff. 0000007023 00000 n Lisinopril is classified as an angiotensin-converting enzyme inhibitor and has been available for nearly three decades. Losratan is FDA-approved to treathypertension. Click here for full Prescribing Information. Losartan is an angiotensin II receptor blocker (ARB) and lisinopril is an angiotensin-converting enzyme inhibitor (ACE inhibitor). Some beta blockers block the two main beta receptors, while others block only one receptor. Hyperkalemia: Hyperkalemia may occur with ENTRESTO. Comment: 235 normotensive IDDM patients with microalbuminuria participated in double-blind, randomised, placebo-controlled trials to assess the effects of captopril 50 mg twice daily on the progression to overt clinical albuminuria. another ACEi (eg, lisinopril 10 mg; ramipril 5 mg)2, Low-dose ARB: CHF: Initial: 40 mg twice daily. In addition to the above, there are some less commonly used ACEi that are listed here with their dose equivalence. symptomatic hypotension. 0000001733 00000 n with ENTRESTO may result in worsening of renal function, including possible acute renal failure. Doing so can cause a dangerous drop in blood pressure. Monitor concentrations with ACE inhibitor co-administration. Losartan is a type of blood pressure medication that works by blocking receptors for angiotensin, an enzyme that can cause blood pressure to increase. 0000001940 00000 n Telmisartan, also available as brand-name Micardis, has better 24-hour coverage than losartan. renal function, concomitant use of non-steroidal anti-inflammatory drugs (NSAIDs), including COX-2 inhibitors,

0000004152 00000 n Benicar (olmesartan) is known as an ARB (Angiotensin Receptor Blocker), and is in the same class of medication as Cozaar (losartan). Keep in mind this is not an all-inclusive list. Do not administer within The generic versions of losartan and valsartan made national headlines this past year when the FDA announced a significant number of recalls after finding carcinogens in both drugs. Whitehouse Station, NJ: Merck & Co, Inc.; December 2005. When indicated, they should be started at low dose and increased gradually to reach the target dose. This site complies with the HONcode standard for trust- worthy health information: verify here. Weight <85kg, heart failure (50mg total daily), Contraindicated in severe liver impairment. heart failure), treatment with ACE inhibitors and angiotensin receptor antagonists has been associated Disclaimer: Starting doses and titration schedule depend on individual clinical scenario and are particularly If you or a loved one took contaminated valsartan and have been diagnosed with cancer, you may be eligible to file a lawsuit today. WebWith the recent valsartan recall, many clinicians are needing to replace it with an equivalent dosage of an alternative angiotensin II receptor blocker. Comment: Meta-analysis concluding that ACE inhibitors improve microalbuminuria in normotensive patients with type 1 diabetes mellitus. Your email address will not be published. Hydrochlorothiazide Combination Medications. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Losartan (Cozaar ) Dosing : Hypertension: Oral: Initial: 25 to 50 mg once daily. 0000030631 00000 n If you need further assistance, please contact Support. Senni M, McMurray JJV, Wachter R, et al. discontinue ENTRESTO. within 36 hours of switching from or to an ACEi, Discover support and resources to help get your patients started on ENTRESTO, * Lisinopril vs Losartan. Huang YH, Wang HT, Zhu QZ, et al. `#3)>dTgX\:H 5db.prBD zWJMA8JuD"j/X3p8y@DB-V`/PP 5em P(j7T;3M gBb5:CxIm^VqYfSN+5"g%'KR\~91/Lc[v6)E -k $9p2w(%|#?ve k*BruVj2)3PA|MFad;8 c7]@=i7X8#z%RL%h1qE@-6K3"o4L0l@ @/rHbS$LXCPT`aM Fv;xXQEHIiVQs/b !dVPW^L>4_b!qQUm K%vq`2 9TJ8|gc4L:>P0,mkJ!Hsf9>o\8^/.TCqgc+G\1V_YZk;kq-l43GvQD :']5"hs mqF&$X yT`wI8h 0000006710 00000 n Angiotensin II is the hormone that 12 0 obj << /Linearized 1 /O 14 /H [ 1238 288 ] /L 120824 /E 104013 /N 2 /T 120466 >> endobj xref 12 40 0000000016 00000 n References. 2012; 28(3):280322. Accessed April 15, 2018. allow for a 36-hour washout period prior to initiating ENTRESTO.1, No starting dose adjustment is needed for mild or moderate renal impairment, No starting dose adjustment is needed for mild hepatic impairment. Lisinopril can be used to treat high blood pressure and heart failure, and to increase survival following a heart attack. Losartan Alternatives 1 Beta Blockers. FDA officials maintain that the higher level of allowed carcinogens will not substantially impact the overall safety of these drugs. As of August 2019, reports show more than 100 lawsuits have been filed in the MDL. The dose in hypertension is 1.25 mg every six hours administered intravenously over a five minute period. This reduces strain on the heart and causes a reduction in blood pressure. Cardiovascular: hypotension (use low dose and titrate slowly in volume contracted patients). Copyright 1993-2021 Dosage reduction or interruption of ENTRESTO may be required. Losartan and valsartan are categorized as angiotensin II receptor blockers (ARBs). Losartan comes only as a tablet you take by mouth. Read more for examples of scenarios that warrant or do not warrant emergent echo. Titrate dose to target of 160 mg twice daily as tolerated. If you are taking losartan you should avoid potassium-containing salt substitutes or View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Therefore switching from ACE inhibitors to ARB might be beneficial in patients at risk or with COVID-19 in prevention of such sequelae when they are already on therapy affecting the Renin-Angiotensin System. These drugs mainly treat hypertension also commonly known as high blood pressure. American Society of Consultant Pharmacists, Inc. HWK6WRZ@\Mp6+E=l~gHp[Pk47kI?$UDy5yR?%f/n< 0000005532 00000 n ENTRESTO [prescribing information]. Is losartan or valsartan more effective? Choose ARBs Over ACE Inhibitors for First-line Hypertension Treatment, Large New Analysis Suggests. The choice of angiotensin-II receptor blocker (also known as angiotensin-II receptor antagonist) usually depends on the person's comorbidities, local recommendations, and cost. DP - Unbound Medicine Enter your email below and we'll resend your username to you. and ACE inhibitors and ARBs act by blocking RAAS with beneficial effects on patients with cardiovascular risk factors only (hypertension, diabetes) and with several heart diseases (heart failure, coronary artery disease). WebThe efficacy and tolerability of a fixed-dose combination of 4 mg perindopril and 5 mg amlodipine, a calcium channel antagonist, has been confirmed in a prospective, observational multicenter trial of 1,250 hypertensive patients. Choose initial dose of ENTRESTO based on current treatment and titrate to the target dose1, Low-dose ACEi: The incidence of cough is Copyright 2021 GlobalRPH - Web Development by, HONcode standard for trust- worthy health. 545 ratings on Drugs.com.

Your email address will not be published. ACE inhibitors may increase the sensitivity to insulin or other antidiabetic agents. Handy reference while reading echos, especially useful for guideline-based prosthetic valve evaluation, Important formulae in cardiology. Hb```f`` @Qk)(#SUfUl I@@X*@eg,azW q#PESAEWA k#O2] mL// @s1A b [& endstream endobj 51 0 obj 176 endobj 14 0 obj << /Type /Page /Parent 9 0 R /Resources 15 0 R /Contents [ 24 0 R 26 0 R 30 0 R 32 0 R 34 0 R 36 0 R 38 0 R 41 0 R ] /Rotate 90 /MediaBox [ 0 0 612 792 ] /CropBox [ 0 0 612 792 ] >> endobj 15 0 obj << /ProcSet [ /PDF /Text /ImageC ] /Font << /TT2 20 0 R /TT4 16 0 R /TT6 21 0 R /TT9 27 0 R >> /XObject << /Im1 39 0 R >> /ExtGState << /GS1 44 0 R >> /ColorSpace << /Cs6 22 0 R >> >> endobj 16 0 obj << /Type /Font /Subtype /TrueType /FirstChar 32 /LastChar 122 /Widths [ 278 0 0 0 0 889 0 0 333 333 0 0 0 333 0 278 556 556 556 556 556 556 0 0 0 0 0 0 0 0 584 0 0 722 722 722 722 667 611 778 722 278 0 0 611 833 722 778 667 778 722 667 611 722 667 0 0 0 611 0 0 0 0 0 0 556 611 556 611 556 333 611 611 278 0 556 278 889 611 611 611 0 389 556 333 611 556 778 556 556 500 ] /Encoding /WinAnsiEncoding /BaseFont /BKCBFI+Arial,Bold /FontDescriptor 18 0 R >> endobj 17 0 obj << /Type /FontDescriptor /Ascent 905 /CapHeight 718 /Descent -211 /Flags 96 /FontBBox [ -517 -325 1082 998 ] /FontName /BKCCOB+Arial,Italic /ItalicAngle -15 /StemV 0 /XHeight 515 /FontFile2 48 0 R >> endobj 18 0 obj << /Type /FontDescriptor /Ascent 905 /CapHeight 718 /Descent -211 /Flags 32 /FontBBox [ -628 -376 2000 1010 ] /FontName /BKCBFI+Arial,Bold /ItalicAngle 0 /StemV 144 /XHeight 515 /FontFile2 43 0 R >> endobj 19 0 obj << /Type /FontDescriptor /Ascent 905 /CapHeight 718 /Descent -211 /Flags 32 /FontBBox [ -665 -325 2000 1006 ] /FontName /BKCBEH+Arial /ItalicAngle 0 /StemV 94 /XHeight 515 /FontFile2 42 0 R >> endobj 20 0 obj << /Type /Font /Subtype /TrueType /FirstChar 32 /LastChar 150 /Widths [ 278 0 0 0 0 0 667 0 333 333 389 0 278 333 278 278 556 556 556 556 556 556 556 556 556 556 278 278 584 0 0 0 0 667 667 722 722 667 0 0 722 278 0 0 556 833 722 778 667 0 722 667 611 722 667 0 667 0 611 0 0 0 0 0 0 556 556 500 556 556 278 556 556 222 0 500 222 833 556 556 556 556 333 500 278 556 500 722 500 500 500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222 0 0 0 556 ] /Encoding /WinAnsiEncoding /BaseFont /BKCBEH+Arial /FontDescriptor 19 0 R >> endobj 21 0 obj << /Type /Font /Subtype /TrueType /FirstChar 32 /LastChar 122 /Widths [ 278 0 0 0 0 0 0 0 333 333 389 0 278 0 0 0 0 0 0 0 0 0 0 0 0 0 278 0 0 0 0 0 0 667 667 722 722 0 0 0 0 0 0 0 556 833 722 778 667 0 722 667 611 722 667 0 667 0 611 0 0 0 0 0 0 556 0 500 556 556 0 0 556 222 0 500 222 833 556 556 556 0 333 500 278 556 500 0 500 500 500 ] /Encoding /WinAnsiEncoding /BaseFont /BKCCOB+Arial,Italic /FontDescriptor 17 0 R >> endobj 22 0 obj [ /ICCBased 45 0 R ] endobj 23 0 obj 1259 endobj 24 0 obj << /Filter /FlateDecode /Length 23 0 R >> stream Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). A total of 376 drugs are known to interact with lisinopril: A total of 303 drugs are known to interact with losartan: ** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. Calcium channel blockers are blood pressure medications designed. Usual dose: 20-40 mg in a single or 2 divided doses. Novartis Pharmaceuticals Corporation. Comment: American Diabetes Association recommendations for management of hypertension in diabetes. Because lisinopril and losartan work to lower your blood pressure, adjusting your dose means your blood pressure can change. Johns Hopkins Guide App for iOS, iPhone, iPad, and Android included. Please review the latest applicable package insert for additional information and possible updates. Do not take more than one dose of medication at a time. Unless your patient is on a high ACEi/ARB dose, start ENTRESTO at 24/26 mg twice daily and double WebLisinopril 20mg Enalapril 20mg Perindopril 4mg Ramipril 10mg Candesartan 16mg 8mg 16mg Irbesartan 150mg Telmisartan 80mg 40-80mg 40mg ~80mg Valsartan 160mg Endocrine/metabolic: gynecomastia, hyperkalemia, Dermatologic: angioedema of face, lips, and throat (0.1%), Hematologic: agranulocytosis, neutropenia. If hypotension persists despite dose adjustment of diuretics, concomitant antihypertensive drugs, and Yancy et al. If angioedema occurs, discontinue ENTRESTO immediately, provide appropriate therapy, and monitor for aliskiren in patients with renal impairment (eGFR <60 mL/min/1.73 m2). Reduced risk of stoke, MI and death Initial: 2.5 mg once daily for first week, then 5 mg once daily for weeks 2-4, then titrate to 10 mg once daily as tolerated. Copyright 1993-2021 Aliskiren enhances the hyperkalemic and nephrotoxic effect of ACE inhibitors, and use of aliskiren with an ACE inhibitor is contraindicated in patients with diabetes.

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